Abstract

Artificial inoculation of turkeys with Mycoplasma meleagridis resulted in an initial IgM response as early as 4 days postinoculation. These antibodies were gradually replaced by IgG beginning 10-14 days postinoculation. The intensity of antibody response was dependent on route of inoculation, with the intravenous route being the most effective, followed by intra-air-sac and intra-sinus inoculation. The serum plate agglutination test was found efficient in detecting IgM antibodies and relatively insensitive in detecting antibodies in IgG fractions. The hemagglutination-inhibition test reacted with IgG antibodies only, and the tube agglutination test was equally effective in detecting antibodies of both classes of immunoglobulins.

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