Abstract
This study identified risk markers for NSCL/P in a Brazilian population. Study Design: The investigation was a structured association study with 16 polymorphisms in 300 NSCL/P patients and 395 controls from Minas Gerais state, plus 7 polymorphisms in 505 patients with NSCL/P and 594 controls from Minas Gerais and Bahia state, Brazil. The polymorphisms were genotyped using the allelic discrimination with fluorescence probes. Ancestry was determined by genotyping 40 bi-allelic short insertion-deletion polymorphisms.
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