Abstract

Snake venoms can affect blood coagulation and platelet function in various ways (1–6). The literature is extensive on the use of snake venoms for elucidating the nature of the mechanisms of blood coagulation and platelet aggregation as well as for the need to understand snake venoms more fully. One of the main attractions for investigators in the field of hemostasis and thrombosis has been the use of venoms and venom components in practical laboratory tests, in clinical use, and more recently, for application in theoretical studies. In this article, the characteristics of snake venom principles affecting blood coagulation and platelet aggregation are reviewed. The mechanisms of action of snake venom principles affecting blood coagulation and platelet aggregation are summarized in Fig. 1.

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