Abstract

To realize a sensitive and low cost optofluidic biosensor, we propose a localized surface plasmon resonance (LSPR) sensor chip based on supported gold nanoparticles (AuNPs). The AuNPs were generated by vacuum thermal evaporation and annealing process. Sample liquids with different concentration were utilized to characterize the sensitivity of the self-assembled AuNPs film. Important issue, one of the advantages of optofluidics can be coupling with LSPR sensors. The LSPR sensor integrated self-assembled continuous flow optofluidics with the flow rate of 50 μl/m showed the sensitivity along with its potential application of simple and low-cost fabrication.

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