Abstract

Fibrous dysplasia (FD) is a rare skeletal disease often associated with McCune-Albright Syndrome (MAS); a triad of FD, café-au-lait skin hyperpigmentation and endocrinopathies. It is caused by activating postzygotic GNAS1 gene mutations. Multiple bones may be affected including maxilla and mandible. Also, endocrinopathies in MAS can further influence bone metabolism.

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