Characterization of Nanofibers Matrix as Extract Media of Dragon’s Blood for Wound Healing

Abstract

Dragon’s blood is traditionally used for treating diarrhea and producing natural dyes. An in vitro study of dragon’s blood ethyl acetate extract showed that it promotes blood coagulation and can heal wounds in rabbits. Its resin extract heals injury in rabbits using PVDF nanofibers matrix as a medicine medium. Therefore, this research aimed to determine the PVDF nanofibers as medicine mediums. The characteristics of the samples were observed using SEM/EDX, FTIR, and X-Ray diffraction. The SEM morphological examination showed that the nanofibers were still clearly visible without the dragon’s blood extract. Furthermore, the higher the concentration of this extract in the sample, the less it becomes. The elements in the PVDF nanofibers matrix are C (carbon) and F (fluorine). Adding dragon’s blood resin extract to the matrix increases the number of elements other than C and F, such as O (oxygen). The infrared spectrum (IR) of the matrix nanofibers absorption peak at about 2921.85 cm-1 is for the vinylidene C-H stretching vibration. Meanwhile, approximately 1400.79 cm-1, 879.11 cm-1, and 839.83 cm-1 are characteristic absorptions of C-F bonds. The nanofibers matrix has a crystallinity of 63.71%, which is then reduced to 41.22% and 35.16%, adding 5% and 10% resin extract, respectively.