Abstract
This study aimed to provide an overview on the HIV-1 subtypes circulating in Slovakia between 2017 and 2018 and to evaluate the risk of transmission of HIV‑resistant strains. The HIV epidemic in Slovakia is characterised by low incidence of new and pre-existing infections and aslightly elevated level of strain heterogeneity. Partial HIV pol gene sequences of 110 individuals newly diagnosed with HIV between 2017 and 2018 were analysed. The genotypic analysis revealed sporadic occurrence of mutations linked to HIV resistance to antiretroviral therapy (ART). The HIV-1 Bsubtype has been found as predominant (84.55%) and primarily linked to men who have sex with men (MSM). Atotal of eighteen individuals (15.45%) were found to be infected with HIV-1 non-B subtypes. The data suggest aminimal risk of aresistant HIV strain transmission and amarginal rise of HIV-1 subtypes´ diversity. The HIV-1 Bsubtype remains the most prevalent in the period 2017-2018 in Slovakia (Tab. 2, Fig. 2, Ref. 37).
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