Characterization of Fatty Acids, Polysaccharides, Amino Acids, and Minerals in Marine Macroalga Chaetomorpha crassa and Evaluation of Their Potentials in Skin Cosmetics.

Haresh S Kalasariya,Virendra Kumar Yadav,Byong-Hun Jeon,Nikunj B Patel,Kahkashan Perveen,Akanksha Yadav,You-Kyung Jung,Faris M Munshi,Shamshad Alam,Krishna Kumar Yadav

doi:10.3390/molecules26247515

Haresh S Kalasariya, Virendra Kumar Yadav + Show 8 more

Open Access

https://doi.org/10.3390/molecules26247515

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Abstract

Cosmetic industries are highly committed to finding natural sources of functional active constituents preferable to safer materials to meet consumers’ demands. Marine macroalgae have diversified bioactive constituents and possess potential benefits in beauty care products. Hence, the present study was carried out to characterize the biochemical profile of marine macroalga Chaetomorpha crassa by using different techniques for revealing its cosmetic potentials. In results, the FTIR study characterized the presence of different bioactive functional groups that are responsible for many skin-beneficial compounds whereas six and fifteen different important phycocompounds were found in GCMS analysis of ethanolic and methanolic extracts, respectively. In the saccharide profile of C. crassa, a total of eight different carbohydrate derivatives were determined by the HRLCMS Q-TOF technique, which showed wide varieties of cosmetic interest. In ICP AES analysis, Si was found to be highest whereas Cu was found to be lowest among other elements. A total of twenty-one amino acids were measured by the HRLCMS-QTOF technique, which revealed the highest amount of the amino acid, Aspartic acid (1207.45 nmol/mL) and tyrosine (106.77 nmol/mL) was found to be the lowest in amount among other amino acids. Their cosmetic potentials have been studied based on previous research studies. The incorporation of seaweed-based bioactive components in cosmetics has been extensively growing due to its skin health-promoting effects.

Highlights

IntroductionAccording to Kerdudo et al [2], hydroxybenzoic acid esters (parabens), which are widely used in cosmetic formulations, were reported as harmful to the skin as well as causing an increased incidence of breast cancer and malignant melanoma
A total six different pounds werewere detected fromfrom the ethanolic extract of Chaetomorpha crassa
The current findings revealed that the Chlorophyta C. crassa is a good source of active ingredients with much cosmetic potential

Summary

Introduction

According to Kerdudo et al [2], hydroxybenzoic acid esters (parabens), which are widely used in cosmetic formulations, were reported as harmful to the skin as well as causing an increased incidence of breast cancer and malignant melanoma. Phthalates, as an example, are commonly found in several cosmetic products that can cause DNA modifications and damage as proved in human sperm cells [3]. Some of these chemicals can cause harmful effects in animal studies such as decreased sperm counts, altered pregnancy outcomes, male genitalia congenital disabilities, etc. The ever-expanding market for skincare products and continual search for an alternative natural ingredient has led to the development of a multitude of skin cosmetic formulations [5]

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