Abstract
EVs, membrane-bound vesicles that mediate proximal and distal intracellular communication,1 have been found in reproductive biofluids1,2 and are thought to influence important pathophysiologic processes including gametogenesis, fertilization, and implantation.1 We hypothesize that characterization of EVs from patients’ follicular fluid (FF) and embryo culture media (CM) can inform ART outcomes.
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