Abstract

Increase in research focus on developing lab-on-chip based devices like Body-on-chip and Organ-on-chip, have led to a higher number of functional entities in lab-on-chip. This, in turn, has led to increasingly complex microfluidic channel networks. Thus, there arises a need to characterize the microfluidic networks and establish communication among various entities of lab-on-chip. Electric circuit analogy is one of the options for the characterization of such a microfluidic network. Further, the dielectrophoresis relay-assisted molecular communication system can help in establishing interconnection among various entities using molecular communication. We propose to use an electrical transmission line technique to model and characterize the dielectrophoresis relay-assisted molecular communication system. We use transmission line parameters- resistance, inductance, and capacitance for characterizing the said molecular communication system. The numerical results obtained show that the peak concentration reduces as a function of distance, and the attenuation of the transmitted signal decreases with the increase in the number of relays in the system. This implies that the dielectrophoresis relay-assisted molecular communication system can help in transmitting low-frequency concentration signal with low attenuation. The results obtained are consistent with those obtained with already existing techniques. Thus, the transmission line technique can be utilized for characterizing a microfluidic system for molecular communication.

Highlights

  • Body-on-chip is a biomimetic microsystem engineered to emulate the structural and functional complexity of the human body

  • TRANSMISSION LINE MODELING we model an inter relay segment of the DEP relay-assisted Molecular communication (MC) system using the transmission line technique

  • NUMERICAL RESULTS we present the results of the DEP relayassisted MC system modeled as a transmission line

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Summary

INTRODUCTION

Body-on-chip is a biomimetic microsystem engineered to emulate the structural and functional complexity of the human body. The presence of microfluidic channels (MFCs) in OOC allows the cells to be exposed to various mechanical forces, which help in organ development, such as tension, compression, and fluid shear stress [2] These biomimetic microsystems are essentially lab-on-chip (LOC) devices, interconnected through a network of MFCs. The interconnection of LOCs through the MFC network. Electric circuit analogy has been used in designing several applications involving concentration and flow in MFC networks. An electric circuit analogy can be used for analyzing frequency-dependent flow by accounting for resistive, capacitive, and inductive properties of MFC [18]. The transmission line is an integral part of communication systems, as it supports the propagation of transverse-electro-magnetic (TEM) waves and transmits a signal from one point to another point [20] It has been used for modeling time-variant flows for various applications involving the solution of diffusion equation [21]–[23].

SYSTEM MODEL
PULSE PROPAGATION IN MICROFLUIDIC CHANNEL
TRANSFER FUNCTION
NUMERICAL RESULTS
CONCLUSION
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