Characterization Of Clinical, Heamogram, Leukogram Changes and Stress Indicator in LSD Infected Cows and OSD Infected Buffaloes in Egypt

Abstract

The limited understanding of the infectious diseases induced stress impedes efforts to establish optimal treatment and control programs to maximize the animal health and production. This study was therefore conducted to characterize the clinical and hematological changes duringLumpy skin disease (LSD) and Oedematous skin disease (OSD) in cows and Egyptian buffaloes respectively. The study was conducted using convenience samples of 90 cows and 35 Egyptian buffaloes during outbreaks in Qalyubia governorate, Egypt. Clinical, bacteriological, and molecular diagnosis of the diseases were performed. Automatic-cell-counter was used for hemogram and leukogram. Serum cortisol concentration was measured using ELISA kits. The statistical significance was set at P < 0.05. The LSD infected cows showed marked decreases in RBCs count, Hb, HCT, WBCs, and lymphocytes, and significant increases in granulocytes, MCV, and MCH compared to the healthy animals. In OSD infected buffaloes, RBCs count, Hb, HCT, WBCs, lymphocytes, granulocytes, MCV, MCH, and MCHC were significantly decreased.Serum cortisol concentration was significantly increased in LSD infected cows and OSD infectedbuffaloes compared to healthy animals. We concluded that LSD and OSD causes injurious shifts in the hemogram, leukogram, and cortisol concentration that indicated deleterious impact on the animal health, production, and well-being.