Characterization of bone remodeling of two different porous types of β-tricalcium phosphates: a quantitative site-by-site analysis using computed tomography.

Abstract

This study compared the process of bone remodeling using spherical porous β-tricalcium phosphate (SPTCP) and unidirectional porous β-tricalcium phosphate (UDPTCP) by quantitative computed tomography (CT) analysis. We retrospectively analyzed the data of 16 patients (4 men, 12 women; age, 43-78years) who underwent medial opening wedge high tibial osteotomy (MOWHTO) and were followed up for 1year postoperatively. Nine patients used SPTCP spacers and seven patients used UDPTCP spacers. CT was performed at 1week, 6months, and 1year postoperatively. CT attenuation values were measured at three sites on the axial slice and sagittal slice, i.e., the superior, center, and inferior sites and the lateral, center, and medial sites for UDPTCP and SPTCP, respectively. CT attenuation values were lower for UDPTCP than for SPTCP in all sites at 6months and 1year postoperatively (p < 0.05). CT attenuation values decreased in the superior and inferior sites for UDPTCP (p < 0.05), and CT attenuation values decreased in the lateral site for both SPTCP and UDPTCP (p < 0.05). The process of bone remodeling differed between the two over a short-term follow-up of 1year postoperatively.