Abstract
Bioactive glass 70SiO2-30CaO (mol.%) was successfully synthesized by modified sol–gel in hot water without using an acid catalyst. TG-DSC analysis showed that the amorphous glass could be synthesized by sintering the sample at 700 °C for three hours. The N2 adsorption/desorption and TEM investigations highlighted that the synthetic glass had a mesoporous structure, consisting of spherical particles with sizes in the range of 11–20 nm. The specific surface area, pore volume, and average pore diameter of synthetic glass were 150.13 m2/g, 0.37 cm3/g, and 11.84 nm, respectively. Moreover, synthetic bioactive glass presented interesting bioactivity and good biocompatibility after in vitro experiments in simulated body fluid (SBF) and in cellular medium.
Highlights
The original bioactive glass was first discovered in 1970 by Larry L
The in vitro experiment was performed by soaking the glass samples in simulated body fluid (SBF) for 1, 3, and 7 days
The bioactive glass synthesized at 700 ◦ C showed broad diffraction halos, characteristic of the amorphous state
Summary
The original bioactive glass was first discovered in 1970 by Larry L. Crystals 2020, 10, 529 wt.%) with and without doping other elements (Sr, Zn, Mg), S53P4 (53SiO2 -20CaO-23Na2 O-4P2 O5 , wt.%), and 13-93 (53SiO2 -20CaO-6Na2 O-12K2 O-5MgO-4P2 O5 , wt.%) The bioactivity of these synthetic glasses have been confirmed in both in vitro and in vivo experiments. Bioactive glass with a composition of 75SiO2 -16CaO-5Na2 O-4P2 O5 (mol.%, noted as S75C16) was successfully synthesized using the sol–gel method without using acid catalysts [11]. A bioactive glass with a composition of 70SiO2 -30CaO (mol.%) was prepared using a hydrothermal method following green synthesis without any acid catalyst [12]. Following the trend of green chemistry, this work reports the preparation of bioactive glass 70SiO2 -30CaO (mol.%) using a modified sol–gel method, in which the reaction mixture was stirred in hot water at a rate of 500 rpm and no acid catalysts were used. The physical–chemical properties and bioactivity of the synthetic glass were investigated
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