Abstract

Knowledge of biological and mechanical properties of native tissues is critical for biomaterial design and synthesis for tissue engineering. So far, selection of biomaterials for dental pulp regeneration has been done randomly or based on experience mainly due to the scarcity of data of biomechanical properties of human dental pulp tissue. This study, for the rst time, characterizes the physical properties of human dental pulp tissue harvested from wisdom teeth, under compression and compared it with PRF and a novel crosslinked PRF (C-PRF) prepared by crosslinking PRF with tannic acid. The results revealed that conventional PRF compressive sterength is very less compared to dental pulp tissue and comparable compressive strength of the novel crosslinked PRF(C-PRF). Taken collectively, crosslinked PRF will better suit for pulp tissue engineering purposes.

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