Abstract
This study aims to characterize and explore the biological effects of melanin derived from nigerseed (Guizotia abyssinica) hulls, which are inedible. Extracted melanin was selectively soluble in alkali and DMSO. The melanin extract demonstrated robust antioxidant and DPPH radical scavenging activities. It exhibited strong antibacterial effects against foodborne pathogens, as indicated by the zone of inhibition (in mm); Salmonella enterica (40.00 ± 0.00), Staphylococcus aureus (37.33 ± 1.15), Micrococcus luteus (31.67 ± 0.58), Klebsiella oxytoca (31.33 ± 1.15), Escherichia coli (30.33 ± 0.58), and Bacillus cereus (28.33 ± 1.15). For antifungal activity, melanin displayed selectivity, suggesting its potential as a targeted antifungal agent. This research highlights nigerseed byproducts as a cost-effective and promising source for melanin production, showcasing its potential in the pharmaceutical sector as a natural alternative to chemically derived drugs.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
