Abstract
In our previous work, a novel polysaccharide APP3a from Auricularia polytricha was successfully isolated and purified. Response surface methodology was used to optimize the preparation process of APP3a-Zn on the basis of the single factor experiments. Characterization of APP3a-Zn was carried out and its antioxidant activity was also investigated. The result showed that the best preparation process of APP3a-Zn was chelation time 4.45 h, chelation temperature 49.37°C and pH 4.68. The weight loss of APP3a-Zn was slightly smaller than that of APP3a within the heating temperature range and the crystal structure of APP3a-Zn had undergone tremendous changes compared with APP3a. APP3a-Zn had stronger antioxidant activity than APP3a. The results indicated that chelation with zinc enhanced the antioxidant activity of APP3a. In the food industry, APP3a-Zn had great potential as a new zinc supplement with antioxidant activity.
Highlights
Zinc (Zn) is one of the essential trace elements in living organisms, which plays an important role in the normal cell function and human metabolism (Beyersmann and Haase, 2001; Wang et al, 2019a)
Zinc deficiency can lead to developmental delays in children, which has become the main cause of public health (Caulfield et al, 2004a; 2004b) and a decline in learning and memory (Boroujeni et al, 2009)
The present study aimed to explore the effect of chelation modification on the antioxidant activity of APP3a-Zn, determine the preparation process of APP3a-Zn and lay the foundation for the development of new biological zinc supplements
Summary
Zinc (Zn) is one of the essential trace elements in living organisms, which plays an important role in the normal cell function and human metabolism (Beyersmann and Haase, 2001; Wang et al, 2019a). Zinc deficiency can cause oxidative damage to the human body because of the inhibition of the formation of Reactive Oxygen Species (ROS) (Harmaza and Slobozhanina, 2014). Zn supplement includes organic zinc (polysaccharide or amino acid chelate) and inorganic zinc (zinc sulfate or zinc oxide). In the case of excessive intake, inorganic zinc has low absorption and toxicity to the human body. It is necessary to develop a safe, effective, long-term and non-toxic zinc supplement agent, which provides an alternative to improve the zinc content in human body
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