Abstract
Characterization and Synthesis of Selenium -TPGS Nanoparticles for Target Delivery Clove to Minimize Cytogenic and Liver Damage Induced in Adult Male Rats
Highlights
The use of herbal medicines and supplements has increased dramatically over the past three decades, with no less than 80 percent of individuals worldwide relying on them for some type of primary health car [1]
The aim of this study is to evaluate the preparation of clove buds by extraction and encapsulation using nanoprecipitation technique with selenium nanoparticles
The nanoparticles are prepared by nanoprecipitation technique and characterized by particles sizers, UV spectrophotometers, and scanning electron microscopy (SEM) images which were utilized for regular distribution and spherical shape of nanoparticles with the size range of 206.5 nm; active compounds were detected by Gas chromatography-mass spectrometry (GC-MS)
Summary
The use of herbal medicines and supplements has increased dramatically over the past three decades, with no less than 80 percent of individuals worldwide relying on them for some type of primary health car [1]. Han and parker [7] reported that S. aromaticum had antiviral, antifungal, antimicrobial, antioxidant, anticancer, and anti-inflammatory properties, due to the active constituent eugenol. Milled material (200 g) was extracted individually with organic solvents with 200 mL ethanol 70% and distilled water using magnetic stirrer with temperature 40 °C and by filtration by filter paper (Whatman No 1). The organic solution including 100 mg of clove was placed in a glass test tube, and transferred 1 mL of acetone solvent, a small piece of aluminum foil, and Parafilm the foil used to close the tube incubated overnight; vortex on high speed until all extract was entity dissolved (~10 min). The supernatant containing the unbound drug was discarded; the pellet obtained was washed 2-3 times with distilled water This step can be conducted using apparatus particle size, UV-visible spectrometry and scanning electron microscope (SEM). Nano zeta sizer (Malvern Instruments, UK) was used
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