Abstract
The aim of this study was to investigate the probiotic potential of bacteriocin-producing lactobacilli strain Lactobacillus plantarum G2 isolated from the vaginal mucus of healthy women. The antimicrobial effect of G2 was confirmed in the mixed culture with pathogenic Escherichia coli, Staphylococcus aureus, Salmonella abony and Pseudomonas aeruginosa, while bacteriocine activity was detected against S. aureus and S. abony only. The strain showed an excellent survival rate in low pH and in the presence of bile salts. The percentage of adhered cells of L. plantarum G2 to hexadecane was 63.85?2.0 indicating the intermediate hydrophobicity.
Highlights
Among lactic acid bacteria members, lactobacilli present a diverse group of homofermentative and heterofermentative species
The Lactobacillus plantarum strain is found to be a normal inhabitant of healthy women (Anukam and Reid, 2007)
According to results it could be speculated that the inhibition of E. coli ATCC 8739 and P. aeruginosa ATCC 9027 is solely a consequence of lactic acid activity
Summary
Among lactic acid bacteria members, lactobacilli present a diverse group of homofermentative and heterofermentative species. Lactobacilli are grampositive rods, primarily facultative or rarely strictly anaerobic bacteria (Kandller and Weiss, 1986; Hammes and Hertel, 2009) that can produce a variety of antimicrobial substances such as lactic acid, ethanol, formic acid, acetone, hydrogen peroxide, diacetyl and bacteriocins. These compounds can serve as a natural competitive means for overcoming other microorganisms sharing the same niche (Oliveira et al, 2008). Lactobacilli are the most important bacteria of the normal vaginal flora of healthy pre-menopausal women and are present at 107-108 CFU/ml of vaginal fluids (Fazeli et al, 2006). The purpose of this study was to investigate several important probiotic features of one vaginal Lactobacillus strain, including its antimicrobial potential, gastric and bile tolerance and cell surface hydrophobicity
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