Abstract
Background. Hypoglycemia is an important complication of the treatment of type 2 diabetes mellitus, which constitutes a barrier in stringent diabetic control. Beside it constitutes nearly 10 % of emergency department admissions that caused by adverse drug events, it may also increase morbidities and mortality by inducing, cardiac arrhythmias, neurological impairment and ischemic events. Hypoglycemia is the most common side effect of insulin treatment, however, oral antidiabetic agents may also induce hypoglycemic complications. In present retrospective study, we purposed to observe general characteristics and laboratory data of the type 2 diabetic patients whom presented with mild or moderate/severe hypoglycemia. Materials and methods. Patients with type 2 diabetes mellitus whom presented to our institution with hypoglycemia between January 2019 and January 2020 were retrospectively analyzed. General characteristics and laboratory data of the subjects recorded. Patients grouped into two groups, group I consisted of subjects with mild hypoglycemia and group II consisted of patients with moderate/severe hypoglycemia. Data of the subjects in groups I and II were compared. Results. There were 15 subjects in group I and 23 in group II. HbA1c and other laboratory markers were not significantly different in study groups. Similarly diabetes duration and anti-diabetic treatment were not significantly different in study groups. The rate of geriatric patients was significantly higher in group II compared to group I (p = 0.04). Conclusions. Subjects with moderate/severe hypoglycemia tend to be more frequently in geriatric age and HbA1c not correlates with the degree of the hypoglycemia. Since neither duration of diabetes, nor anti-diabetic treatment were associated with the severity of the hypoglycemia, each case should be evaluated individually to prevent further episodes which could increase morbidity and mortality in diabetic population.
Highlights
Hypoglycemia is an important barrier for tight glucose control during treatment of diabetic subjects since it is a severe and life threatening acute complication of anti-diabetic therapy [1]
Beside it constitutes nearly 10 % of emergency department admissions that caused by adverse drug events [2], it may increase morbidities and mortality by inducing, cardiac arrhythmias, neurological impairment and ischemic events [3]
A plasma glucose level equal to or lower than 70 mg/dl is referred as hypoglycemia according to the suggestions of American Diabetes Association [5]
Summary
Hypoglycemia is an important barrier for tight glucose control during treatment of diabetic subjects since it is a severe and life threatening acute complication of anti-diabetic therapy [1] Beside it constitutes nearly 10 % of emergency department admissions that caused by adverse drug events [2], it may increase morbidities and mortality by inducing, cardiac arrhythmias, neurological impairment and ischemic events [3]. Hypoglycemia is an important complication of the treatment of type 2 diabetes mellitus, which constitutes a barrier in stringent diabetic control Beside it constitutes nearly 10 % of emergency department admissions that caused by adverse drug events, it may increase morbidities and mortality by inducing, cardiac arrhythmias, neurological impairment and ischemic events.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
