Abstract

Background: Hirschsprung's disease is a developmental disorder of the enteric nervous system of the distal intestines. Colon in-loop examination is used as a spearhead in the diagnosis of Hirschsprung's disease, and according to previous studies, it was found that the presence of transitional zone and rectosigmoid index of less than 1 were correlated with positive pathology results in 79%-87% of cases. The purpose of this study was to provide an overview of the rectosigmoid index of patients suspected of having Hirchsprung's disease as illustrated by a colon in-loop examination. Methods: The research method is cross-sectional descriptive from January 2018 to December 2019 at Prof. Dr. dr. I. G. N. G. Ngoerah Hospital Denpasar. Data collected from colon in-loop examination in patients suspected of having Hirschsprung's disease included gender, age, RSI, and pathology results in patients who underwent biopsy. Data were analyzed using SPSS version 20 for Windows. Results: The results found from 49 samples were that Hirschsprung was dominant in males (63.27%). Patients aged less than 1 month were the most common, with a percentage of 44.9%. The second most common was at the age of 1 to 12 months at 30.6%, while the incidence rate with the least number was at the age of more than 12 months, namely 24.5%. RSI data found that of the patients suspected of having Hirschsprung's disease, 40 samples, or 81.6%, had an RSI < 1, and it was found that of the 40 samples with RSI < 1, 82.9% confirmed Hirschsprung's with an aganglionic pathology result. In contrast, in patients with aganglionic PA, the proportion of patients with RSI < 1 was more than 80%. Conclusion: The data obtained in this study are in accordance with those described in previous studies and support the role of RSI in strengthening the diagnosis of Hirschsprung's disease.

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