Abstract
Objective To investigate the changes of multifocal electroretinogram (mf-ERG) in type 2 diabetes without clinically apparent retinopathy.Methods Eighteen type 2 diabetes patients (32 eyes) without clinically observed retinopathy and 14 normal control eyes received mf-ERG examination.Results The latency of P1 wave in the ring one,ring two and ring three of diabetes were (48.47 ± 2.33),(31.19 ± 15.53),(15.67 ± 5.73) ms respectively,which had significantly statistical difference with the normal control eyes (t 5.145,2.376,2.276;P＜ 0.05).The amplitude density of P1 wave of temporal retina in diabetes patients was (9.07 ± 2.19) nV/deg2,which was significant different (t=-3.468,P＜0.05) with the normal control eyes (14.13 ± 2.76) nV/deg2.Conclusion The latency of mf-ERG P1 wave is delayed,and the amplitude density of P1 wave of temporal retina is declined in type 2 diabetes patients without clinically apparent retinopathy. Key words: Diabetic retinopathy/diagnosis; Electroretinography
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