CHARACTERISTICS OF THE LIPID PROFIL YOUNG ADULTS WITH ISCHEMIC HEART DISEASE IN GEORGIAN POPULATION

Abstract

Objective: Impaired lipoprotein metabolism is a significant and modifiable risk factor for atherosclerotic cardiovascular disease. Aim: The aim of our study was to determine the diagnostic accuracy of lipid profile indices in young adults in Georgian population. Methods: Under our observation were 107 patients with ischemic heart disease, aged 18-45 years, From the St. John The Merciful Private Clinic contingent. Examination: anamnesis, cardiography, echocardiography, coronography, blood lipid metabolism. Total cholesterol (TC), high-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol (LDL), Triglycerides (TG), mmol/L) and lipid indices -TC-HDL/HDL, TG /HDL, and LDL/HDL Results: With IHD for young adults, TC-HDL/HDL distinguished by good sensitivity and sufficient specificity, TG /HDL - bad sensitivity and very excellent specificity, LDL/HDL - sufficient sensitivity and good specificity, With IHD, for TC-HDL/HDL Cut off=2.29, for TG /HDL, cut off=2.76 and for LDL/HDL - 2.17 High lipid indices on these data indicate a high risk of ischemic heart disease. Conclusion: lipid indices TC-HDL/HDL, TG /HDL, and LDL/HDL can be used for the primary diagnosis of ischemic heart disease in young adults. Keywords: risk factors IHD, dyslipidemia.