Abstract
Changes in external respiration and central hemodynamics induced by negative (relative to atmospheric) inspiration pressure were studied in supine subjects before and on the fourth day of a dry immersion (DI) experiment. Changes in the cardiorespiratory system as a result of negative inspiration pressure included an increase in the amplitude of breathing motions and reduction of their frequency, and distinct breathing-related HR fluctuations. Combinations of immersion and altered pressure in the mask caused breathing-related variations of systolic pressure and plethysmogram signal, and improved arterial blood oxygenation. These results could be useful for developing pressure-gradient methods of counteracting adverse effects of blood redistribution toward the cranial end.
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