Characteristics of the degrees of severity of the course of acute intestinal infection in elderly patients with COVID-19

Abstract

The article discloses the characteristics of the degrees of severity of acute intestinal infection in elderly and senile patients with COVID-19.
 The aim of the article is to substantiate the characteristics of the degrees of severity of acute intestinal infection (AII) in elderly and senile patients with COVID-19.
 Materials and methods. Conditionally pathogenic microorganisms were detected in the patients of the study group by the bacteriological method. The WHO age classification was used to estimate age. The presence of the definition of a coronavirus infection and comorbid conditions was ascertained based on the following methods: selection of indicators of the immunoenzymatic method, PCR test, measurements the degree of saturation of arterial blood with oxygen by pulse oximetry, heart rate, temperature marks, questionnaires NEWS and ABCD for monitoring the dynamics of the disease in patients. Dehydration scale (CDS) was used to determine the severity of acute intestinal infection.
 The Charlson comorbidity index was used to characterize comorbid conditions. Statistical methods were used: the Kolmagorov-Smirnov test, the non-parametric Wald Wolfowitz test. The obtained results were performed using the Statistica 13 Trial program. The severity index of COVID-19 has been determined, with the help of which it is possible to identify and sort patients to identify complications and a quick algorithm for the doctor's actions and the conditions of the intensive care unit.
 The results. Several indicators of the modified NEWS questionnaire were determined, which confirm that the age of patients ≥ 65 years is associated with a more severe course of the disease. It has been established that such comorbid conditions as: damage to peripheral vessels, dementia, the presence of peptic ulcer disease are associated with a milder course of GKI against the background of COVID-19. The incidence of diabetes without damage to the limbs is reliably associated with a more severe course of the disease. Analyzing the indicators of the ABCD system, namely: age of patients, laboratory and instrumental tests, pantry poor conditions, risk factors associated with the severity of the course of COVID-19 were assessed.
 Conclusions. The total result of the Charlson comorbidity index was determined in patients with AII on the background of COVID-19. The results confirm that such patients have a higher probability and risk of mortality.
 A direct moderate correlation has been proven between the total result of the NEWS questionnaire and the course of AII, which indicates a higher frequency of the formation of severe forms of the latter in the presence of higher values of the questionnaire and the corresponding more severe course of COVID-19. The results of the severity index of COVID-19 allow us to conclude that the data are associated with an increase in the severity of acute intestinal infection in elderly patients