Abstract

Statistical analyses on DNA microarray expression data have made it possible to extract information from tissue and cell samples. Recently, Support Vector Machines (SVMs)[3], one of the supervised learning methods, have been employed to classify gene expression data and have shown greater performance than other learning methods, especially in the case where the number of features is larger than the number of samples[1]. However, the characteristics of SVMs are not clear. Thus, in this work, we will study how the number of features and regulatable parameters on SVMs affect performance of classification on DNA microarray. Gene expression profiles derive from various types of cancers using Affymetrix GeneChip, including our institute sample data.

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