Abstract
This cohort study compares the characteristics of infections from SARS-CoV-2 variants spreading during August to October 2020 vs the variants spreading during December 2020 to February 2021 among children in Israel.
Highlights
Since December 2020, the SARS-CoV-2 B.1.1.7 variant has been spreading in Israel, and by January or February 2021 it quickly became the predominant circulating strain, isolated in more than 80% of cases.[1]
Data were analyzed for 21 615 children aged 0 to 9 years (50.9% male children) who had positive SARS-CoV-2 polymerase chain reaction tests between August 1 to October 2, 2020, and for 50 811 children aged 0 to 9 years (51.5% male children) who tested positive between December 3, 2020, and February 3, 2021
The percentage of hospitalized children with unfavorable outcomes out of total number of hospitalizations was not different between the 2 periods. These results demonstrate that SARS-CoV-2 spread more effectively and more rapidly among young children during the time of B.1.1.7 variant circulation in Israel
Summary
Since December 2020, the SARS-CoV-2 B.1.1.7 variant has been spreading in Israel, and by January or February 2021 it quickly became the predominant circulating strain, isolated in more than 80% of cases.[1]. The aim of this study was to compare the characteristics of SARS-CoV-2 spread in children, aged 0 to 9 years, in 2 periods when different SARS-CoV-2 variants were circulating: August to October 2020, when former SARS-CoV-2 variants (mostly GH and GR clades)[2] circulated, and December 2020 to February 2021 since the introduction of the B.1.1.7 variant in Israel
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