Characteristics of progressive temporal visual field defects in patients with myopia

Jiyun Lee,Kyoung In Jung,Chan Kee Park

doi:10.1038/s41598-021-88832-1

Jiyun Lee, Kyoung In Jung + Show 1 more

Open Access

https://doi.org/10.1038/s41598-021-88832-1

Copy DOI

Abstract

Temporal visual field damage (VFD) is the common type of non-glaucomatous VF defects found in eyes with myopia. However, little is known about the factors associated with its progression. We investigated the characteristic of myopic eyes with progressive temporal VF defects. This retrospective, observational study included a total of 116 eyes: 39 eyes with temporal VFDs and an axial length greater than 24.5 mm, 77 eyes with typical glaucomatous VFDs who were followed up more than 5 years. VF progression was evaluated with Trend-based global progression analysis. In the temporal VFD group, the greater tilt ratios, the higher prevalence of β-zone peripapillary atrophy (β-PPA), the substantial increase in β-PPA were found, compared to the typical glaucomatous VFD groups (all P-values ≤ 0.001). The temporal VFD group had the slower progression than the typical glaucomatous VFD group on trend-based GPA (P = 0.047). In the multivariate linear regression analysis, the change of β-PPA area over years was related to temporal VFD progression (B, − 0.000088, P = 0.003). In conclusion, myopic eyes with the temporal VFD, which come with growing β-PPA area, should be monitored with extra caution.

Highlights

Temporal visual field damage (VFD) is the common type of non-glaucomatous VF defects found in eyes with myopia
Myopic eyes undergo the elongation of the posterior segment, and this elongation would result in structural changes to the optic nerve head (ONH) including tilt, torsion, and peripapillary atrophy (PPA)[5,6,7]
As for glaucoma medication, more than two third of the temporal VFD group was on glaucoma medication, the percentage of the patient and the number of the eyedrops were substantially lower compared to typical glaucomatous group

Summary

Introduction

Temporal visual field damage (VFD) is the common type of non-glaucomatous VF defects found in eyes with myopia. We investigated the characteristic of myopic eyes with progressive temporal VF defects This retrospective, observational study included a total of 116 eyes: 39 eyes with temporal VFDs and an axial length greater than 24.5 mm, 77 eyes with typical glaucomatous VFDs who were followed up more than 5 years. When myopic patients present with stereotypical glaucomatous VFDs, the diagnosis is relatively easy and treatment can be initiated without hesitation When it comes to atypical VFDs accompanied by structural myopic changes in the ONH, it is hard to decide whether the patient needs treatment. The temporal VFD is not regarded as a typical type of the VFDs

Methods

Results

Discussion

Conclusion