Abstract
Introduction: The differentiated thyroid cancer has generally an excellent prognosis after the treatment. The aim of this study is to describe the characteristics of persistent or recurrent differentiated thyroid cancers. Patients/ Methods: It is about a descriptive and retrospective study conducted from 392 patients followed for differentiated thyroid cancer. The data concerning the persistent or recurrent differentiated thyroid cancer have been collected from 1986 to 2015 in endocrinology service in Ibn Rochd CHU. Results: In total, twenty-four patients have shown the relapse or the persistency of their tumor, corresponding to the prevalence of 6.12 percent. The papillary carcinoma was dominant in 79 percent of cases and the follicular carcinoma in 21 percent of cases. The metastases were cerebral (two cases), lung (3 cases), bones (3 cases, Figure 1), and lymph nodes (9 cases). In our series, eighteen cases of persistent differentiated thyroid cancer have been found against six cases of recurrent differentiated thyroid cancer. Two cases of death at least three years of followed in our series and concerned the two cases of cerebral metastasis. Conclusion: The persistent or recurrent differentiated thyroid cancer rate is low in our series. The discovery of the relapse t is late.
Highlights
The differentiated thyroid cancer has generally an excellent prognosis after the treatment
The aim of this study is to describe the characteristics of persistent or recurrent differentiated thyroid cancers
The papillary carcinoma was dominant in 79 percent of cases and the follicular carcinoma in 21 percent of cases
Summary
The differentiated thyroid cancer has generally an excellent prognosis after the treatment but the life expectancy of patients is reduced to sixty percent in persistent or recurrent differentiated thyroid cancer. This was related to patients lost to follow-up and inaccessibility of diagnostic tools. The data concerning the persistent or recurrent differentiated thyroid cancer have been collected from 1986 to 2015 in endocrinology service in Ibn Rochd CHU in Casablanca. The recurrent of differentiated thyroid cancer specifies itself as the appearance of the clinical and/or biological and/or radiological manifestations of differentiated thyroid cancers after a year of initial treatment. The persistency of differentiated thyroid cancer means a positive thyroglobulin and/or the expansion of the anti-thyroglobulin antibody and/or the radiologic highlighting of the tumor/swelling in the twelve months that followed the initial treatment. The analysis of the data has been made by the software SPSS 20.0
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