Characteristics of peripheral blood parameters in patients with COVID-19-associated pneumonia

Abstract

The new coronavirus infection caused by the SARS-CoV-2 virus has become a serious problem worldwide. COVID-19 is primarily a respiratory tract infection. Viral lung damage caused by SARS CoV-2 is commonly interpreted as COVID-19-associated pneumonia. Patients with severe course of the disease have more pronounced violations of laboratory blood parameters. A general blood test of patients with COVID-19associated pneumonia refers to non-specific laboratory diagnostic methods and at the same time plays an important role in assessing the severity of the condition, as well as allows predicting the course, development and outcome of the disease. The aim of the study was to study peripheral blood counts in hospitalized patients with COVID-19-associated pneumonia. A retrospective analysis of the medical histories of patients with COVID-19 associated pneumonia was carried out. The presence of the SARS-Cov-2 virus was confirmed by polymerase chain reaction. The examination of patients was carried out according to the current protocol "Coronavirus infection COVID-19 in adults". Hematological parameters in patients with moderate and severe pneumonia were analyzed. CT-2 and CT-3 predominated in terms of lung tissue damage. The results of the study revealed changes in the general analysis of peripheral blood, such as a decrease in lymphoid cells, the absence of reactive leukocytosis to acute inflammation, and thrombocytopenia. The changes depended on the severity of pneumonia and the presence of concomitant pathologies.