Abstract

Tongue cancer is one of the leading sites of cancer in our population. To evaluate the socio-demographic profiles and stages at diagnosis of oral tongue (OT) and base of tongue (BT) cancers, and identify any possible variations in characteristics. A retrospective analysis was conducted on tongue cancer cases, divided into OT and BT, registered at the hospital cancer registry of North-East India during January 2010 to May 2013. Cases were analyzed for age, gender, residential status and different levels of education for patients, the stage at diagnosis and presence of distant metastasis. A total of 1,113 cases of tongue cancers were registered, 846(76.1%) of BT and 267(23.9%) of OT. While 33.9% of BT cancer patients were above 65 years of age, the figure for OT cancers was 18.4%, stages III and IV accounting for 90.8% and 77%, respectively. The relative risk for distant metastasis in OT cancers was 3.3 (95% CI 1.08-10.1, p=0.03). In the subsites of tongue cancers in our population, the majority arose from the base of tongue, these tending to occur in older individuals and presenting at late stage.

Highlights

  • Tongue cancer is one of the common cancers in users of chewable tobacco and alcohol

  • Majority of cases of base of tongue (BT) cancer occurred above 65 years (287/846,33.9%) followed by, in the age group of 55-64 years (236/847,27.8%), and for oral tongue (OT) cancers majority were seen in the age group of 45-54 years (71/267,26.5%) followed by in the age group of 55-64 years (70/267,26.2%) (Figure1)

  • OT cancer which is likely to be seen due to the use of chewable tobacco and poor oral hygiene was seen in 24% of cases of tongue cancer in this analysis

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Summary

Introduction

Tongue cancer is one of the common cancers in users of chewable tobacco and alcohol. In addition to risk factors like tobacco and alcohol there is a growing interest in the role of human papilloma virus (HPV) infection in cancers of the oral cavity and tongue in particular. The aims of the present study were to evaluate the socio-demographic and stages at diagnosis of OT and BT cancers, and identify any possible variations in its characteristics. Aim: To evaluate the socio-demographic profiles and stages at diagnosis of oral tongue (OT) and base of tongue (BT) cancers, and identify any possible variations in characteristics. Cases were analyzed for age, gender, residential status and different levels of education for patients, the stage at diagnosis and presence of distant metastasis. Conclusions: In the subsites of tongue cancers in our population, the majority arose from the base of tongue, these tending to occur in older individuals and presenting at late stage

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