Abstract

Some publications have evaluated mineral oils (MO) and paraffin oils based on labeling as light or heavy, terms which have been used to describe either density or viscosity, and as MO or liquid paraffin (LP). Such studies tested mouse embryo development, pH, osmolality, temperature, viscosity, density, and peroxide value. MO and light mineral oil (LMO), defined in the United States Pharmacopeia, and LP and light liquid paraffin (LLP), defined in the European Pharmacopoeia have requirements for viscosity and density but the defined ranges don’t align exactly. All four are defined as mixtures of hydrocarbons. This work characterizes the hydrocarbon molecule sizes in the samples to evaluate similarities between MO, LMO, LP, and LLP with their overlapping definitions.

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