Abstract
BackgroundTo summarize the characteristics of solitary necrotic nodules (SNN) in the liver observed under contrast-enhanced ultrasonography (CEUS).MethodsConventional ultrasonography (US) and CEUS were performed in 24 patients who were confirmed to have SNN by pathological assessment. The US data and dynamic enhancement patterns of CEUS were recorded and retrospectively analyzed.ResultsTen of 24 patients underwent surgical resection, while the other 14 patients underwent a puncture biopsy to be confirmed as SNN. Among the 24 patients, 13 patients had a single lesion and 11 patients had multiple lesions. The largest lesion was selected for CEUS examination for patients with multiple lesions. Eleven patients presented no enhancement in all three phases, while the other 13 patients presented with a peripheral thin rim-like enhancement in the arterial phase, an iso-enhancement in the portal phase and delayed phase. However, no enhancement in the interior of the lesions was detected during three phases of CEUS.ConclusionsSNN has characteristic findings on the CEUS, which play an important role in the differential diagnoses of liver focal lesions.
Highlights
To summarize the characteristics of solitary necrotic nodules (SNN) in the liver observed under contrast-enhanced ultrasonography (CEUS)
Fifteen cases were examined by physical examination or hospitalized for other extrahepatic diseases, 2 patients were complicated with abdominal distension, and 7 patients had a history of malignant tumor (2 cases of breast cancer, 3 cases of colon cancer and 2 cases of hepatocellular carcinoma)
Patient diagnosis and outcomes All the patients were confirmed as SNN by pathological results, with 10 patients undergoing surgical resection and 14 patients undergoing a puncture biopsy
Summary
To summarize the characteristics of solitary necrotic nodules (SNN) in the liver observed under contrast-enhanced ultrasonography (CEUS). With the wide application of contrast-enhanced ultrasonography (CEUS) in the diagnosis of liver lesions, some hepatic lesions could be qualitatively diagnosed by the enhancement pattern observed under CEUS [5]. This could be helpful to improve the differential diagnosis of hepatic lesions by comparing the difference in blood perfusion between the lesion and its surrounding normal liver parenchyma. Since few studies have identified features of SNN on the CEUS for a differential diagnosis.
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