Abstract
Background: ADR (Adverse drug reactions) is also known as an adverse drug effect. ADRs of anti-tuberculosis drugs are quite common, causing changes in haematological tests. Objective: to study the characteristics of some haematological index and peripheral blood cell morphology in pulmonary tuberculosis patients with tuberculosis drugs with ADR who were treated at the National Lung Hospital from January 2021 to June 2021. Subjects and methods: 134 patients with pulmonary tuberculosis were diagnosed with tuberculosis drugs with ADR at the National Lung Hospital using a cross-sectional descriptive study. Results showed that the mean erythrocyte index was 3.69±0.92x1012/l in men and 3.81±0.74x1012/l in women, mean haemoglobin was 102.42±26.44 g/l in men and 96±22.81 g/l in women. The rate of anaemia was 73.47% in men and 61.11% in women. Average white blood cell count was 11.88±6.38x109/l, average platelet index was 371.45±198.16x109/l. Common morphology: roulaux cells, target cells and hypochromic RBCs. Neutrophils increase segmentation and granulocytosis. Giant platelets. Conclusion: pulmonary tuberculosis patients with tuberculosis drugs with ADR have anaemia, appearance of granulocytosis, giant platelets, rouleaux cells, target cells and hypochromic RBCs.
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