Characteristics of Gestational Trophoblastic Disease at Indonesian National Referral Hospitals: A Literature Review

Abstract

Gestational trophoblastic disease (GTD) is a pregnancy disorder due to an abnormality of the placenta, such as enlargement of the chorionic villi. The spectrum of GTD may range from benign to malignant. Characteristics of the gestational trophoblastic disease have been discussed in the literature. This study discussed the characteristics that resulted from previous studies and the relationship of those characteristics and gestational trophoblastic disease. The results of this study revealed that there were five national referral hospitals in Indonesia which discussed the clinical characteristics in their report on gestational trophoblastic disease, namely age, marital age, gestational age, number of parity, patients educational level, patients and husband job, haemoglobin levels, region of origin, ethnicity, referral cases, complaints, pregnancy intervals, β-hCG levels, pregnancy history, length of stay, treatment duration, histopathology finding, staging/scoring, metastases, treatment, complications, and contraceptives. Out of the 25 characteristics that has been analyzed, 16 were studied to determine their relationships to gestational trophoblastic disease, while the other 9 were only analyzed descriptively.