Characteristics of a Post-Coronavirus-19 Sample Undergoing Rehabilitation: An Exploratory Study

Abstract

<h3>Research Objectives</h3> Describe sample presenting to a brain rehabilitation clinic with cognitive impairment after COVID-19 infection. <h3>Design</h3> Pre- and post-intervention measures from a clinical sample. <h3>Setting</h3> Outpatient Brain Rehabilitation Clinic. <h3>Participants</h3> Eight patients undergoing outpatient rehabilitation after COVID-19 infection (Mean age = 47.1, Range: 38-55 years; females = 6, males = 2; 4 hospitalized at time of acute infection, Mean time to treatment 243 days, Range: 84-415 days). <h3>Interventions</h3> Treatment by an experienced team of interdisciplinary providers with composition and treatment frequency tailored to individual needs. <h3>Main Outcome Measures</h3> Patient Health Questionnaire (PHQ-9); Participation Index of the Mayo-Portland Adaptability Inventory (M2PI); Satisfaction with Life Scale (SWLS); Neurobehavioral Symptom Inventory – 22 (NSI-22). <h3>Results</h3> Average number visits = 6.5 (Range: 0-25). Treatment attendance was close to 100%. Mean PHQ-9 on admission 10.625 (Range: 3-18) and at discharge 10.25 (Range: 1-17). Mean M2PI on admission was 13 (Range:8-24, and on discharge was 10.875 (Range: 0-20). Mean SWLS was the same at admission and discharge, 20.625 (Range: Admit: 15-29, Discharge 10-29). NSI-22 mean on admission 37.375 (Range 16-49) and on discharge 31.5 (Range:6-54). <h3>Conclusions</h3> Most of our sample reported moderate to moderate-severe depression. Most endorsed moderate-severe disability on the M2PI. This changed only slightly over treatment. This sample reported highly variable symptom complaint and life satisfaction. Of 5 patients with worsening scores over treatment, 4 were patients who started treatment well over 200 days after their initial diagnosis (Range: 229-415 days). Our treatment sample reports variable symptomatology and outcomes that may be tied to time to initiating rehabilitation. <h3>Author(s) Disclosures</h3> None.