Characteristics and treatment of pediatric malignant solid tumor in Guangxi

Abstract

Objective To explore the clinical data of the pediatric malignant solid tumor and to summarize the experiences of the pediatric malignant solid tumor treatment in Guangxi. Methods The clinical data of 323 cases of pediatric malinant solid tumor, treated surgically in the First Affiliated Hospital of Guangxi Medical University from Dec.1988 to Dec. 2008. Pathology, sex, age, clinical characteristics, diagnosis and treatment were analysed respectively. Results The most frequent histological types were malignant lymphoma, Wilms tumor, neuroblastoma and malignant germ cell tumor. There was a male prevalence with a sex-ratio of 1.99∶1. The peak incidence in embryo tumor was under 3 years, and epithelium cancer was between the ages of 10-13 years. The main symptoms were palpable mass(56.3) and a few were found in health examination; 64.2% of the pediatric malignant solid tumor was of stage Ⅲ or Ⅳ; the complete tumor resection rate was 78.4%. Conclusions The characteristics of pediatric malignant solid tumor is different from those of adults. To detect as soon as possible and treat the pediatric malignant tumor as soon as possible depends on screening. Combined modality therapy can improve the patients complete resection rate and survival quality of the patients. Key words: Pediatric malignant solid tumor; Characteristic; Treatment experience