CHARACTERISTICS AND RESULTS OF TREATMENT OF HYPERTRIGLYCERIDEMIA-INDUCED ACUTE PANCREATITIS AT CAN THO UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL

Abstract

Background: After alcohol and gallstones, hypertriglyceridemia is the third most common cause of acute pancreatitis (AP). Hypertriglyceridemia is triglyceridemia concentration >150mg/dl (1.7mmol/l). Severe hypertriglyceridemia >1000mg/dl (11.3 mmol/l) is considered the cause of AP. Objectives: To compare some clinical and subclinical features and results of treatment of AP with two levels of hypertriglyceridemia <11.3mmol/l and >I1.3mmol/l at the Department of General Internal Medicine in Can Tho University of Medicine and Pharmacy Hospital. Materials and methods: This was a cross-sectional descriptive study of 33 patients who were admitted to the hospital with hypertriglyceridemia-induced AP. Results: Clinical symptoms and some laboratory tests did not differ between the two groups. Statistically significant differences occurred in the 2 groups as blood CRP value with p=0.009, low sodium levels 134.22±4.73mmol/l and high BMI levels 26.63±5.15kg/m2 in the group with TG ≥ 11.3 mmol/l. The rate of amylase increased 3 times in the high-TG group was 85.2%. Both groups had elevated glucose and LDH levels respectively, with 10.56±5.13 mmol/l and 310.64±206.01U/L. Ultrasound diagnosis of acute pancreatitis reached 100%, CTSI and BISAP index were high in the group with TG ≥11.3mmol/l. The days of using insulin and staying in the hospital were significantly different, with p=0.004 and p=0.014. Conclusions: Comparing the 2 groups of acute pancreatitis with blood TG <11.3mmol/l and ≥11.3mmol/l, there was no difference in clinical symptoms. Mean values of sodium, BMI and blood CRP (p=0.009) were different between the two groups of acute pancreatitis. Treatment results in days of using insulin and staying in the hospital had statistically significant differences between the 2 groups.