Abstract

To describe and analyze the epidemiological characteristics of lung cancer mortality in China from 1991 to 2013, forecast the future five-year trend and provide scientific evidence for prevention and management of lung cancer. Mortality data for lung cancer in China from 1991 to 2013 were used to describe epidemiological characteristics. Trend surface analysis was applied to analyze the geographical distribution of lung cancer. Four models, curve estimation, time series modeling, gray modeling (GM) and joinpoint regression, were performed to forecast the trend for the future. Since 1991 the mortality rate of lung cancer increased yearly. The rate for males was higher than that for females and rates in urban areas were higher than in rural areas. In addition, our results showed that the trend will continue to increase in the ensuing 5 years. The mortality rate increased from age 45-50 and peaked in the group of 85 years old. Geographical analysis indicated that people living in northeast China provinces and the coastal provinces in eastern China had a higher mortality rate for lung cancer than those living in the centre or western Chinese provinces. The standardized mortality rate of lung cancer has constantly increased from 1991 to 2013, and been predicted to continue in the ensuing 5 years. Further efforts should be concentrated on education of the general public to increase prevention and early detection. Much better prevention and management is needed in high mortality areas (northeastern and eastern parts of China) and high risk populations (45-50-year-olds).

Highlights

  • Lung cancer accounts for the largest number of cancerrelated deaths in China and throughout the world (World Health Organization, 2012)

  • The World Health Organization estimates that the annual lung cancer mortality rate in China may reach 1 million by 2025

  • We use monitoring data of cancer mortality rate in China for the period 1991-2013 to describe the dynamics of death, sex, age, urban-rural location, and geographic distribution of lung cancer to determine lung cancer prevention strategies in China

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Summary

Introduction

Lung cancer accounts for the largest number of cancerrelated deaths in China and throughout the world (World Health Organization, 2012). Timely and accurate data on cancer are essential for effective lung cancer control. An accurate knowledge of lung cancer patterns and their development trend in the future are essential in the planning of national cancer control programs (Wei et al, 2012). We use monitoring data of cancer mortality rate in China for the period 1991-2013 to describe the dynamics of death, sex, age, urban-rural location, and geographic distribution of lung cancer to determine lung cancer prevention strategies in China. Prediction of the trends and identification of geographic patterns of lung cancer mortality, based on population and location, may provide important clues regarding the cause and effect of the relevant factors. We used trend surface analysis, one of the most widely used to reflect geographical distribution and trends of disease, to describe the geographical distribution of lung cancer mortality rate in China

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