Abstract

Background: To date, many countries/regions around the world have reported Patients with COVID-19, which is an acute respiratory inflammatory disease caused by a new strain of the coronavirus.The aim of this study is to evaluate the treatment efficacy of COVID -19 patients at the Hue Central Hospital-branch 2. Methods: Twenty four COVID-19 patients transferred from Da Nang were included in the study. Results: There was no statistically significant difference in age and sex between men and women (p> 0.05). There were 16patients (66.67%) with chronic renal failure (CRF) accounting for the highest proportion, 12 patients (50%) with hypertension (HYP), 06 patients (25%) with type 2 diabetes (diabetes), 06 patients (25%) with exacerbation of chronic obstructive pulmonary disease (COPD), 04 cases (16.67%) with cancer, 09 cases (37.50%) with 02 chronic diseases, 05 cases (20.83%) with 03 chronic diseases, 1 case (4.17%) with 04 chronic diseases. The average concentration of D-dimer was extremelyhigh (9057.38+154.34 ng/mL). 14 COVID-19 patients (58.33%) had mechanical ventilation, 09 patients (37.50%) were on hemodialysis cycle, 09 patients (29.17%) were on continuous renal replacement therapy (CRRT), 3 patients (12.50%) were on dialysis ECMO, 12 patients must use vasopressors (Noradrenalin, Adrenalin, Dobutamine). The Mortality was equal to the survival rate. Conclusion: The extremely elevated plasma D-dimer concentration is one of the high-risk factors for mortality in COVID-19 patients. COVID-19 old Patients who also suffer from chronic diseases such as hypertension, obesity, type 2 diabetes, coronary artery disease, chronic kidney failure are highly associated with the increased mortality rate.

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