CHARACTERISTIC TIME PARAMETERS OF THE ORGANISM’S REACTION TO OXYGEN SUPPLY DYNAMICS OF TISSUES AND THEIR EXPERIMENTAL DETERMINATION

Abstract

The paper studied the dynamics of the partial pressure of oxygen in the subcutaneous tissues with a limited load and further postischemic hyperemia in healthy people and those with abnormalities of lower limbs.On the basis of theoretical and experimental studies established criteria of optimality main parameters of the oxygen supply system of the subcutaneous tissues in a transient mode. It was noted that the transcutaneous control of pO2 of the affected vessels of the lower extremities at different loads, makes it possible to objectively assess the oxygen status of subcutaneous tissues and judge the functional state of the peripheral blood flow of the affected vessels.It is shown that parameters such as time and the characteristic relaxation time of self-oxygen content in the intercellular fluid, characterize the functional state of the body.An experimental method for determining these time parameters is proposed and it is shown that they have a close connection with the stage of pathological changes in the body