Abstract
Microcrystalline Cellulose (MCC) is a modified of cellulose widely used as an additive in food and pharmaceutical industry. MCC is used in the pharmaceutical field as an excipient compound in the manufacture of tablets. Raw materials for MCC are of high cellulose content, such as Eucheuma cottonii seaweed. This study was aimed to determine the characteristics of MCC from seaweed E. cottonii. The MCC was obtained by hydrolyzing of α-cellulose from seaweed E. cottonii using HCl solution with three different concentrations: 2, 2.5 and 3 N. The chemical compositions (water, ash, protein, lipid, and carbohydrate) of red seaweed flour were determined. The moisture, ash, sensory, yield, and pH of the MCC were also analysed. The results showed that E. cottonii seaweed flour had moisture, protein, fat, ash, and carbohydrate content 3.88%, 0.85%, 2.4%, 3.44%, and 89.4% respectively. HCl concentrations had a significant effect on the moisture and ash content. The MCC had a yield of 35.8-38.00%, pH 5.73-6.82, moisture content 4.09.6, ash 0.94-4.90%. The characteristics of the MCC was in accordance with the standards of the British Pharmacopeia except the ash content.
Highlights
Abstrak Microcrystalline Cellulose (MCC) merupakan modifikasi selulosa yang berfungsi sebagai bahan tambahan banyak digunakan dalam industri pangan dan farmasi
Characteristic of Microcrystalline Cellulose from Red Seaweed Eucheuma cottonii Abstract Microcrystalline Cellulose (MCC) is a modified of cellulose widely used as an additive in food and pharmaceutical industry
Raw materials for MCC are of high cellulose content, such as Eucheuma cottonii seaweed
Summary
Cara sitasi: Edison, Diharmi A, Sari ED. 2019. Karakteristik selulosa mikrokristalin dari rumput laut merah Eucheuma cottonii. Abstrak Microcrystalline Cellulose (MCC) merupakan modifikasi selulosa yang berfungsi sebagai bahan tambahan banyak digunakan dalam industri pangan dan farmasi. Bahan baku untuk MCC adalah bahan yang mengandung kadar selulosa tinggi salah satunya berasal dari rumput jenis Eucheuma cottonii. Metode penelitian adalah mengisolasi MCC dengan cara hidrolisis α-selulosa dari rumput laut E. cottonii menggunakan larutan HCl dengan tiga konsentrasi berbeda yaitu 2, 2,5 dan 3 N. Hasil penelitian menunjukkan tepung rumput laut E. cottonii memiliki kadar air, protein, lemak, abu, dan karbohidrat berturut-turut 3,88%, 0,85%, 2,4%, 3,44%, dan 89,4%. Hasil analisis MCC yang dihasilkan dengan konsentrasi HCl yang berbeda berpengaruh nyata terhadap kadar air dan kadar abu. Penelitian menyatakan bahwa dengan konsentrasi HCl yang digunakan dalam proses hidrolisis limbah pada nata de coco menjadi mikrokristalin selulosa yaitu berkisar antara 1N sampai dengan 3N (Pane 2014). Rumput laut memiliki kandungan senyawa α-selulosa yang dapat dimanfaatkan sebagai bahan baku MCC. Penelitian ini bertujuan menentukan karakteristik MCC dari rumput laut E. cottonii
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