Abstract
The viscosity behaviour and physical properties of blends containing hyaluronic acid (HA) and poly(N-vinylpyrrolidone) (PVP) were studied by the viscometric technique, steady shear tests, tensile tests and infrared spectroscopy. Viscometric and rheological measurements were carried out using blends of HA/PVP with different HA weight fractions (0, 0.2, 0.5, 0.8 and 1). The polymer films and HA/PVP blend films were prepared using the solution casting method. The study of HA blends by viscometry showed that HA/PVP was miscible with the exception of the blend with high HA content. HA and its blends showed a shear-thinning flow behaviour. The non-Newtonian indices (n) of HA/PVP blends were calculated by the Ostwald–de Waele equation, indicating a shear-thinning effect in which pseudoplasticity increased with increasing HA contents. Mechanical properties, such as tensile strength and elongation at the break, were higher for HA/PVP films with wHA = 0.5 compared to those with higher HA contents. The elongation at the break of HA/PVP blend films displayed a pronounced increase compared to HA films. Moreover, infrared analysis confirmed the existence of interactions between HA and PVP. The blending of HA with PVP generated films with elasticity and better properties than homopolymer films.
Highlights
Faculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarin 7, 87-100 Toruń, Poland; Citation: Lewandowska, K.; Szulc, Abstract: The viscosity behaviour and physical properties of blends containing hyaluronic acid (HA)
Viscometric and rheological measurements are commonly employed for the characterisation of polymer fluids [1,2,3,4,5,6,7]
Hyaluronic acid (HA) is a natural, polyanionic polysaccharide produced from natural sources, including strains of Streptococcus bacteria, rooster combs, marine animals, etc
Summary
Faculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarin 7, 87-100 Toruń, Poland; Citation: Lewandowska, K.; Szulc, Abstract: The viscosity behaviour and physical properties of blends containing hyaluronic acid (HA). The non-Newtonian indices (n) of HA/PVP blends were calculated by the Ostwald–de Waele equation, indicating a shear-thinning effect in which pseudoplasticity increased with increasing HA contents. Mechanical properties, such as tensile strength and elongation at the break, were higher for HA/PVP films with wHA = 0.5 compared to those with higher HA contents. Miscibility of polymers in solution is a vital indicator for the physical and surface properties of a blend It is a significant aspect for the production of new functional materials based on the mixing of biopolymers with other components.
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