Abstract
The conserved extracellular vesicles (EVs)‐miRNAs from milk might potentially influence human gene expression, or even introduce their analogous nucleotide chains into the human food chain. This study aimed to characterise the features of Brown Swiss milk EVs and the EVs‐miRNAs profile. Brown Swiss milk EVs exhibited a cup‐shaped morphology, with a distribution of (2.3 ± 0.8) E + 11 particles/mL. Sequencing identified a total of 238 miRNAs, which were mainly implicated in immune response and cell signal transduction. The conservation of these milk EVs‐miRNAs among species suggested they might be evolutionarily selected to regulate the growth and development of the newborns.
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