Abstract
Soon after its publication in German, Markovnikov's Rule attracted the attention of the Belgian organic chemist, Louis Henry, who challenged Markovnikov's observation. Its vindication for western chemists was largely due to the work of Arthur Michael. The unpredictability of the addition of hydrogen bromide to alkenes was explained by the radical mechanism of Morris Kharasch. The reversal of the concept of Markovnikov's Rule by Frank Westheimer's mechanistic research led to the coining of the term, "anti-Markovnikov," which has had unfortunate pedagogical consequences.
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