Abstract

Ketenes are typically highly reactive compounds, undergoing addition reactions with electrophiles and nucleophiles as well as being subjected to [2 + 2] cycloadditions with double bonds, providing a wide variety of desired products. The most characteristic reactions of ketenes involve [2 + 2] cycloadditions to numerous double bonds such as CC, CO, CS, NO, and NN to produce the corresponding heterocycles. This chapter, as a Part 1, covers the advances and applications of ketenes in the syntheses of three- and four-membered heterocycles.

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