Abstract
Synthetic cannabinoids (SCs) are cannabimimetic compounds that represent a large and diverse class of novel psychoactive substances. SCs can exert full- or even super-agonist activity at cannabinoid receptors, while Δ9-tetrahydrocannabinol (THC), the main psychoactive phytocannabinoid in cannabis, has weak, partial agonist activity at cannabinoid receptors. SCs may therefore have higher addictive liability than natural cannabis. SC consumption has been associated with psychotomimetic effects, the induction of psychotic disorders, and other clinically relevant effects of acute toxicity. These conditions are qualitatively and quantitatively different from those observed after cannabis intake, with SC ingestion also being associated with increasing numbers of confirmed fatalities.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
More From: The Complex Connection between Cannabis and Schizophrenia
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.