Abstract

This chapter outlines the interactions of clay minerals with nucleic acids. Adsorption of nucleic acids to clay minerals is effected through electrostatic interactions, cation bridging and ligand exchange. The latter bonding mode is important with kaolinite and allophane. Adsorption declines as solution pH increases from acid to alkaline but is enhanced in the presence of neutral electrolytes and polyvalent cations. Nucleic acids can intercalate into montmorillonite at pH < 6. Adsorption also leads to a change in molecular conformation. Clay-associated DNA may be amplified through the polymerase chain reaction and is capable of transforming competent cells. Montmorillonite can catalyse the formation of RNA from its activated monomers.

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