Abstract

Idiopathic pulmonary fibrosis (IPF) is a complex disease that is limited to the lungs. The natural history of IPF is one of slow and progressive decline in lung function with most patients dying from respiratory failure within 2–5years of diagnosis. Several clinical factors can be helpful in predicting prognosis. Changes in symptoms, pulmonary physiology, and chest imaging can be used as markers and are helpful in predicting survival. With the advent of two antifibrotic medications, the disease course of IPF may be altered, with a slower decline in lung function, a delay in time to acute exacerbations, and an increase in survival time.

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