Abstract
Progress in science depends on new ideas, new discoveries, and new techniques, and often the three are interdependent. Nowhere is this more apparent than in the two techniques, DNA sequencing and polymerase chain reaction (PCR), that were born out of creative ideas and rapidly gave rise to an explosion of fundamental and applied discoveries. Sanger developed the first practical DNA sequencing method. The basic idea of the PCR method is to take a very small amount of DNA and make billions of identical copies of it. The DNA sequencing and PCR methods are carefully explained.
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