Abstract
Pharmacogenomics is one of the cornerstones for implementation of precision medicine. Recent studies indicate that one in four primary care patients is prescribed at least one medication that commonly causes adverse drug reactions due to genetic variability in drug metabolism. Very few studies, however, have focused on implementation of precision medicine and pharmacogenomics in primary care. An example of the potential for precision medicine in primary care is warfarin, a widely prescribed and extremely effective anticoagulant, used in the prevention of embolic strokes in patients with atrial fibrillation that is associated with a high rate of bleeding events. With the maturing of warfarin dosing algorithms over the last several years and with easier access to cheaper and faster genotyping techniques, family physicians can use this information to help prescribe warfarin more accurately and safely however little genomics testing has been introduced into primary care. In this chapter we present a feasibility study that was conducted in a family medicine clinic.
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